Chakraborty, Tushar Kanti ; Mohan, Bajjuri Krishna ; Sreekanth, Midde (2006) Studies directed towards the synthesis of antascomicin A: stereoselective synthesis of the C22-C34 fragment of the molecule Tetrahedron Letters, 47 (29). pp. 5003-5005. ISSN 0040-4039
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2006.05.115
Abstract
A stereoselective synthesis of the C22-C34 fragment of the non-immunosuppressive immunophilin-binding natural product, antascomicin A was achieved using d-quinic acid as the starting material and highly stereoselective aldol reactions were employed, as key steps, to build the remaining stereocentres at C23, C26 and C27.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Antascomicin; Immunosuppressant; FKBP12 Binding Ligand; Aldol Reaction |
| ID Code: | 20509 |
| Deposited On: | 20 Nov 2010 14:24 |
| Last Modified: | 20 Nov 2010 14:24 |
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