Chakraborty, Tushar Kanti ; Sudhakar, Gangarajula (2006) Total synthesis of (+)-conagenin Tetrahedron Letters, 47 (33). pp. 5847-5849. ISSN 0040-4039
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2006.06.087
Abstract
The total synthesis of the immunomodulator, (+)-conagenin was achieved using, as a key step, a method developed by us for the synthesis of 2-methyl-1,3-diols via Ti(III)-mediated diastereo- and regioselective opening of trisubstituted 2,3-epoxy alcohols, to carry out the stereoselective construction of its pentanoic acid segment.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Conagenin; Epoxide Opening; 2-Methyl-1; 3-diol; Immunomodulator |
| ID Code: | 20505 |
| Deposited On: | 20 Nov 2010 14:24 |
| Last Modified: | 20 Nov 2010 14:24 |
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