Growth of hydroxyapatite on physiologically clotted fibrin capped gold nanoparticles

Sastry, T. P. ; Sundaraseelan, J. ; Swarnalatha, K. ; Liji Sobhana, S. S. ; Uma Makheswari, M. ; Sekar, S. ; Mandal, A. B. (2008) Growth of hydroxyapatite on physiologically clotted fibrin capped gold nanoparticles Nanotechnology, 19 (24). 245604_1-245604_5. ISSN 0957-4484

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Official URL: http://iopscience.iop.org/0957-4484/19/24/245604

Related URL: http://dx.doi.org/10.1088/0957-4484/19/24/245604

Abstract

The growth of hydroxyapatite (HAp) on physiologically clotted fibrin (PCF)-gold nanoparticles is presented for the first time by employing a wet precipitation method. Fourier transform infrared (FTIR) spectroscopy confirmed the characteristic functionalities of PCF and HAp in the PCF-Au-HAp nanocomposite. Scanning electron microscopy (SEM) images have shown cuboidal nanostructures having a size in the range of 70-300 nm of HAp, whereas 2-50 nm sized particles were visualized in high-resolution transmission electron microscopy (TEM). Energy-dispersive X-ray (EDX) and X-ray diffraction (XRD) studies have confirmed the presence of HAp. These results show that gold nanoparticles with PCF acted as a matrix for the growth of HAp, and that PCF-Au-HAp nanocomposite is expected to have better osteoinductive properties.

Item Type:Article
Source:Copyright of this article belongs to Institute of Physics Publishing.
ID Code:19636
Deposited On:22 Nov 2010 12:15
Last Modified:06 Jun 2011 10:14

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