Evidence for dominant suppression of repeat-induced point mutation (RIP) in crosses with the wild-isolated Neurospora crassa strains Sugartown and Adiopodoume-7

Noubissi, Felicite K. ; Aparna, K. ; McCluskey, Kevin ; Kasbekar, Durgadas P. (2001) Evidence for dominant suppression of repeat-induced point mutation (RIP) in crosses with the wild-isolated Neurospora crassa strains Sugartown and Adiopodoume-7 Journal of Genetics, 80 (2). pp. 55-61. ISSN 0022-1333

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Official URL: http://www.ias.ac.in/jgenet/Vol80No2/55.pdf

Related URL: http://dx.doi.org/10.1007/BF02728331

Abstract

A convenient assay to score repeat-induced point mutation (RIP) in Neurospora employs the erg-3 locus as a mutagenesis target. Using this assay we screened 132 wild-isolated Neurospora crassa strains for ability to dominantly suppress RIP. RIP was exceptionally inefficient in crosses with the wild isolates Sugartown (P0854) and Adiopodoume-7 (P4305), thereby suggesting the presence of dominant RIP suppressors in these strains. In other experiments, we found no evidence for dominant RIP suppression by the Spore killer haplotypes Sk-2 and Sk-3.

Item Type:Article
Source:Copyright of this article belongs to Indian Academy of Sciences.
Keywords:Spore Killer; Meiotic Drive; Neurospora crassa; RIP
ID Code:18351
Deposited On:17 Nov 2010 09:28
Last Modified:17 May 2016 03:04

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