Response to thymectomy in South Indian patients with myasthenia gravis

Narayan, S. K. ; Sarada, C. ; Radhakrishnan, K. ; Nair, M. D. ; Kartha, C. C. ; Neelakandhan, K. S. ; Tharakan, K. J. (1996) Response to thymectomy in South Indian patients with myasthenia gravis Acta Neurologica Scandinavica, 94 (1). pp. 63-66. ISSN 0001-6314

Full text not available from this repository.

Official URL:

Related URL:


Aims - The rate of remission among patients with myasthenia gravis (MG) following thymectomy and the predictors of the outcome have revealed vast variation in studies from different geographic regions raising suspicion about the influence of ethnic factors. Material & methods - We retrospectively evaluated the outcome of 71 South Indian MG patients who were thymectomized between 1987 through 1993 and analyzed the relationship between clinical and histopathological features and postthymectomy outcome. Results - The clinical severity of the disease did not differ between the 29 patients with and 42 patients without a thymoma. Seventynine percent of our patients responded favourably to thymectomy; without additional immunosupression therapy, 52% achieved a near-complete remission. An younger age and milder disease correlated with a good outcome. Patients with thymoma responded as favourably as those without a thymoma. Conclusions - The postthymectomy response of South Indian MG patients in general did not differ from that of Western and Oriental patients.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons, Inc.
Keywords:Myasthenia; Thymoma; Thymectomy
ID Code:18255
Deposited On:17 Nov 2010 12:54
Last Modified:04 Jun 2011 08:30

Repository Staff Only: item control page