Roy, Basab ; Chakraborty, Arindam ; Ghosh, Sudip K. ; Basak, Amit (2009) Design, synthesis and bioactivity of catechin/epicatechin and 2-azetidinone derived chimeric molecules Bioorganic & Medicinal Chemistry Letters, 19 (24). pp. 7007-7010. ISSN 0960-894X
Full text not available from this repository.
Official URL: http://linkinghub.elsevier.com/retrieve/pii/S09608...
Related URL: http://dx.doi.org/10.1016/j.bmcl.2009.04.084
Abstract
A new class of chimeric molecules have been developed. These are based on polyphenols like catechin and epicatechin and monocyclic β-lactams. The two units are joined via a triazole linker using the 'Click Chemistry' conditions. The compounds showed good to weak antibacterial activity against Escherichia coli as well as moderate inhibition of RNase A.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Chimeric; Catechin; Epicatechin; Beta Lactam; Click Reaction; Inhibition |
| ID Code: | 1794 |
| Deposited On: | 05 Oct 2010 12:00 |
| Last Modified: | 12 Jan 2011 11:12 |
Repository Staff Only: item control page
