Kalele, S. A. ; Ashtaputre, S. S. ; Hebalkar, N. Y. ; Gosavi, S. W. ; Deobagkar, D. N. ; Deobagkar, D. D. ; Kulkarni, S. K. (2005) Optical detection of antibody using silica-silver core-shell particles Chemical Physics Letters, 404 (1-3). pp. 136-141. ISSN 0009-2614
Full text not available from this repository.
Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00092...
Related URL: http://dx.doi.org/10.1016/j.cplett.2005.01.064
Abstract
Nearly monodispersed spherical particles of silica were synthesized and coated with thin layer of silver nanoparticles. Silver coated silica particles, forming core-shell particles exhibited a strong surface plasmon resonance peak at 453 nm. A very small amount (20 μg) of rabbit immunoglobulin in core-shell particle solution results in to a marked shift in surface plasmon resonance. Addition of 20 μg quantity of goat anti rabbit antibodies results in to a red shift of surface plasmon resonance to 494 nm. This demonstrates that silver coated silica particles are sensitive probes for rapid antibody-anti antibody kind of interaction investigations. Fourier transform infra red spectroscopy and scanning electron microscopy have been used to interpret the optical extinction spectroscopy results.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 17936 |
| Deposited On: | 17 Nov 2010 13:29 |
| Last Modified: | 04 Jun 2011 08:43 |
Repository Staff Only: item control page
