Laser Raman spectroscopic studies on the interaction of drug Dapsone with model membranes

Abstract

Amphiphilic molecules like model membranes exhibit several special properties because of their ability to undergo co-operative aggregation in aqueous systems. The special properties of such aggregates have made them very important in several applications in industry, basic sciences and advanced technology. To understand the interaction of these systems at a molecular level it is necessary to study several processes. Laser Raman spectroscopy is a convenient technique for gaining information at a molecular level on such systems. In the present paper the applications of laser Raman spectroscopy for the study of these systems are discussed with particular reference to the changes in conformation, identification of structural groups involved in various interactions, arrangement or packing of the amphiphiles in the solid, gel or solution phase, and the effect of additives.