Molecular recognition in β-lactams: the crystal packing in 4-sulfonyl β-lactams

Basak, Amit ; Bag, Subhendu Sekhar ; Mazumdar, Pooja Anjali ; Valerio, Bertolasi ; Kumar, Amit (2004) Molecular recognition in β-lactams: the crystal packing in 4-sulfonyl β-lactams Journal of Chemical Research, 2004 (5). pp. 318-321. ISSN 0308-2342

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Official URL: http://www.ingentaconnect.com/content/stl/jcr/2004...

Related URL: http://dx.doi.org/10.3184/0308234041639647

Abstract

DasSingle crystal X-ray structures of 4-phenyl sulfonyl 2-azetidinone 1, a 1:2 conglomerate of the corresponding 3-methyl (trans) and 3,3-dimethyl derivatives 2A and 2B/2C respectively and 3-acetoxymethyl 1,4-diphenyl 2-azetidinone 3 revealed interesting variation in crystal packing dictated by H-bonding and hydrophobic interactions which may be responsible for molecular recognition in β-lactams.

Item Type:Article
Source:Copyright of this article belongs to Science Reviews Ltd.
Keywords:β-lactams; Crystal Packing
ID Code:1770
Deposited On:05 Oct 2010 12:02
Last Modified:13 Jan 2011 10:49

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