Design, synthesis and DNA-cleaving efficiency of photoswitchable dimeric azobenzene-based C2-symmetric enediynes

Basak, Amit ; Mitra, Debarati ; Kar, Moumita ; Biradha, Kumar (2008) Design, synthesis and DNA-cleaving efficiency of photoswitchable dimeric azobenzene-based C2-symmetric enediynes Chemical Communications (26). pp. 3067-3069. ISSN 1359-7345

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Official URL: http://www.rsc.org/publishing/journals/CC/article....

Related URL: http://dx.doi.org/10.1039/b801644e

Abstract

Designed azobenzene-based enediyne-amino acid C2-symmetric hybrids have been synthesized and the role of amino acid linker in stabilizing the Z form has been demonstrated; DNA-binding and cleavage studies have established higher reactivity of the Z-isomers.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry.
ID Code:1756
Deposited On:05 Oct 2010 11:13
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