Prabhakaran, E. N. ; Rajesh, V. ; Dubey, Shalini ; Iqbal, Javed (2001) Synthesis of cyclic peptides as mimics for the constrained conformation of structural analogues of HIV protease inhibitors Tetrahedron Letters, 42 (2). pp. 339-342. ISSN 0040-4039
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...
Related URL: http://dx.doi.org/10.1016/S0040-4039(00)01951-1
Abstract
A γ-turn induced cyclisation of tripeptides 4 can be performed in a ring-closing metathesis reaction using Grubb's catalyst to the corresponding cyclic peptides 5. These cyclic peptides mimic the constrained conformation of structural analogues of potential HIV protease inhibitors.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 17102 |
| Deposited On: | 16 Nov 2010 08:30 |
| Last Modified: | 17 Feb 2011 05:06 |
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