Polyaniline supported cobalt(II) salen catalysed synthesis of pyrrolidine containing α-hydroxyamide core structures as inhibitors for HIV proteases

Punniyamurthy, T. ; Iqbal, Javed (1997) Polyaniline supported cobalt(II) salen catalysed synthesis of pyrrolidine containing α-hydroxyamide core structures as inhibitors for HIV proteases Tetrahedron Letters, 38 (25). pp. 4463-4466. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/S0040-4039(97)00902-7

Abstract

A novel synthesis of pyrrolidine containing α-hydroxyamide core structures as inhibitors for HIV protease is developed by employing polyaniline supported cobalt (II) salen catalysed formation of the epoxide from cinnamoylamides of L-proline followed by its opening with anilines at ambient condition.

Item Type:Article
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ID Code:17089
Deposited On:16 Nov 2010 08:32
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