Cobalt(II) chloride catalysed conversion of allylic alcohols to rearranged allylic amides

Nayyar, Naresh K. ; Madhava Reddy, M. ; Iqbal, Javed (1991) Cobalt(II) chloride catalysed conversion of allylic alcohols to rearranged allylic amides Tetrahedron Letters, 32 (47). pp. 6965-6968. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/004040...

Related URL: http://dx.doi.org/10.1016/0040-4039(91)80456-G

Abstract

Secondary and tertiary allylic alcohols can be converted to the corresponding allylically rearranged amides and acetates in presence of a catalytic quantity of cobalt(II) chloride and acetic anhydride in acetonitrile. Tertiary alcohols undergo complete rearrangement whereas the secondary ones yield a mixture of regioisomers.

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