Targeting of urea stibamine encapsulated in liposomes to reticuloendothelial system for the treatment of experimental leishmaniasis

Das, Nirmalendu ; Mahato, Sashi B. ; Naskar, Khudiram ; Ghosh, Dilip K. ; Basu, M. K. (1990) Targeting of urea stibamine encapsulated in liposomes to reticuloendothelial system for the treatment of experimental leishmaniasis Biochemical Medicine and Metabolic Biology, 43 (2). pp. 133-139. ISSN 0885-4505

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/088545...

Related URL: http://dx.doi.org/10.1016/0885-4505(90)90018-V

Abstract

The antileishmanial antimonial drug urea stibamine was encapsulated in mannosylated and nonmannosylated liposomes and was tested against experimental leishmanial infection in hamsters. The study demonstrated that liposome encapsulation of urea stibamine enhanced its effectiveness, an effect which was greater when mannosylated liposomes were used.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:1688
Deposited On:05 Oct 2010 12:07
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