Shukla, S. P. ; Kanungo, M. S. (1970) Oxidation of pyruvate and lactate by the liver and brain homogenates of rats of various ages Experimental Gerontology, 5 (2). pp. 171-175. ISSN 0531-5565
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/053155...
Related URL: http://dx.doi.org/10.1016/0531-5565(70)90006-9
Abstract
Oxygen uptake by the liver and brain homogenates of 1-day and 4-, 12-, 30-, 63- and 96-week-old female rats was studied manometrically using pyruvate and lactate as substrates. The rate of uptake increased up to 12 weeks in liver and only up to 4 weeks in brain with either substrate. The was significant decline at high ages. The decreased rates of oxidation of these substrates in old age may be due to changes in the enzymes responsible for their metabolism.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 16370 |
| Deposited On: | 15 Nov 2010 13:46 |
| Last Modified: | 03 Jun 2011 09:28 |
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