Immune response studies in relation to protection induced by using Mdp as an adjuvant in malaria

Khullar, Neeraj ; Gupta, C. M. ; Sehgal, S. (1988) Immune response studies in relation to protection induced by using Mdp as an adjuvant in malaria Immunological Investigations, 17 (1). pp. 1-17. ISSN 0882-1039

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Official URL: http://informahealthcare.com/doi/abs/10.3109/08820...

Related URL: http://dx.doi.org/10.3109/08820138809055714

Abstract

Muramyl dipeptide (MDP) was an important compound conferring protection to mice against the lethal malaria parasite Plasmodium berghei The mode of protection of this compound was studied using different humoral and cellular parameters. The observations indicate that MDP boosts both humoral antibody response as well as delayed type hypersensitivity reactions, but as far as phagocytosis by macrophages is concerned, malarial mice are already maximally stimulated and MDP makes a marginal difference in immune phagocytosis only.

Item Type:Article
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ID Code:15993
Deposited On:16 Nov 2010 13:36
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