Reaction of β-oxodithioesters with propargylamine: a facile entry to novel 2-(acylalkylidene)-5-(methylene)thiazolidines

Chandrasekharam, M. ; Singh, O. Mukherjee ; Ila, H. ; Junjappa, H. (1988) Reaction of β-oxodithioesters with propargylamine: a facile entry to novel 2-(acylalkylidene)-5-(methylene)thiazolidines Synthetic Communications, 28 (16). pp. 3073-3079. ISSN 0039-7911

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Related URL: http://dx.doi.org/10.1080/00397919808004887

Abstract

Reaction of β-oxodithioesters derived from acyclic and cyclic ketones with propargylamine affords novel 2-(acylalkylidene)-5-(methylene)-thiazolidines in high yields by intramolecular nucleophilic attack of thiocarbonyl sulfur on the triple bond of the β-oxo-N-propargylthioamide intermediates.

Item Type:Article
Source:Copyright of this article belongs to Taylor and Francis Ltd.
ID Code:15348
Deposited On:13 Nov 2010 09:29
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