α-Oxoketene dithioacetals mediated heteroaromatic annulation protocol for benzoheterocycles: an efficient regiocontrolled synthesis of highly substituted and annulated indazoles

Peruncheralathana, S. ; Khan, T. A. ; Ila, H. ; Junjappa, H. (2004) α-Oxoketene dithioacetals mediated heteroaromatic annulation protocol for benzoheterocycles: an efficient regiocontrolled synthesis of highly substituted and annulated indazoles Tetrahedron, 60 (15). pp. 3457-3464. ISSN 0040-4020

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/j.tet.2004.02.029

Abstract

An efficient regiocontrolled synthesis of highly substituted and annulated indazoles involving base induced addition-elimination of 1,3-diphenyl-5-cyanomethylpyrazole to a variety of acyclic and cyclic α-oxoketene, followed by acid assisted cycloaromatization of the resulting conjugate adducts has been reported.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:α-oxoketene Dithioacetals; Heteroaromatic Annulation; Benzoheterocycles; Indazoles
ID Code:15284
Deposited On:13 Nov 2010 13:00
Last Modified:03 Jun 2011 04:46

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