Characterization of a 38 kDa penicillin-binding protein and its possible involvement in maintaining stationary-phase cells of Shigella dysenteriae

Mahapatra, Sebabrata ; Basu, Joyoti ; Beeumen, Josef van ; Kundu, Manikuntala (1994) Characterization of a 38 kDa penicillin-binding protein and its possible involvement in maintaining stationary-phase cells of Shigella dysenteriae Microbiology, 140 (11). pp. 3177-3182. ISSN 1350-0872

[img]
Preview
PDF - Publisher Version
2MB

Official URL: http://mic.sgmjournals.org/cgi/content/abstract/14...

Related URL: http://dx.doi.org/10.1099/13500872-140-11-3177

Abstract

This paper reports the first attempt to characterize the penicillin-binding proteins (PBPs) of Shigella dysenteriae, an important human pathogen. The PBP pattern of the membranes of S. dysenteriae closely resembles that of Escherichia coli membranes. A 38 kDa PBP which is an important target for the penem SCH34343, the cephamycin cefoxitin and the oxacephem moxalactam, has been purified. This PBP is immunologically related to a PBP of similar molecular mass in E. coli and is present at high levels in stationary-phase cells of S. dysenteriae.

Item Type:Article
Source:Copyright of this article belongs to Society for General Microbiology.
Keywords:Penicillin-binding Protein; Shigella dysenteriae; Beta-lactam Antibiotic
ID Code:1525
Deposited On:05 Oct 2010 06:41
Last Modified:16 May 2016 12:38

Repository Staff Only: item control page