Facile synthesis of 5-(substituted vinyl)-uracil derivatives through knoevenagel and stobbe type condensations of 5-formyluracils

Harjit Singh, ; Dolly, ; Chimni, Swapandeep Singh ; Kumar, Subodh (1998) Facile synthesis of 5-(substituted vinyl)-uracil derivatives through knoevenagel and stobbe type condensations of 5-formyluracils Journal of Chemical Research (9). pp. 544-545. ISSN 0308-2342

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Official URL: http://pubs.rsc.org/en/Content/ArticleLanding/1998...

Related URL: http://dx.doi.org/10.1039/A802515K

Abstract

5-Formyl-1,3-dimethyl/1,3,6-trimethyl uracils (1) react with malononitrile, ethyl cyanoacetate, phenyl acetonitrile/acetyl acetone in Knoevenagel and with diethyl/dimethyl malonates in Stobbe modes to provide respective 5-(ethoxy/methoxy carbonyl)vinyluracils.

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