Studies towards the total synthesis of Phostriecin

Kumar, Gavireddy Chaithanya ; Muralikrishna, Katta ; Satyanarayana, Vavilapalli ; Kumar, Chintakrinda Suresh ; Yadav, Jhillu Singh (2018) Studies towards the total synthesis of Phostriecin Tetrahedron Letters, 59 (5). pp. 454-456. ISSN 0040-4039

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Official URL: http://doi.org/10.1016/j.tetlet.2017.12.068

Related URL: http://dx.doi.org/10.1016/j.tetlet.2017.12.068

Abstract

A synthetic approach toward the phostriecin, an antitumor natural product is described. The key features of the present synthesis are Wittig reaction, synthesis of homoallylic alcohol using Brown’s protocol (alkoxyallylboration) and RCM for the creation of unsaturated lactone moiety of phostriecin.

Item Type:Article
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ID Code:135679
Deposited On:10 Aug 2023 07:29
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