FRET-Based Probe for Monitoring pH Changes in Lipid-Dense Region of Hct116 Cells

Reddy G, Upendar ; A, Anila H. ; Ali, Firoj ; Taye, Nandaraj ; Chattopadhyay, Samit ; Das, Amitava (2015) FRET-Based Probe for Monitoring pH Changes in Lipid-Dense Region of Hct116 Cells Organic Letters, 17 (22). pp. 5532-5535. ISSN 1523-7060

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Official URL: http://doi.org/10.1021/acs.orglett.5b02568

Related URL: http://dx.doi.org/10.1021/acs.orglett.5b02568

Abstract

A rhodamine conjugate (L) with a pseudo Stokes shift of 165 nm is used for probing changes in solution pH under physiological conditions. This reagent is found to be nontoxic, and the luminescence response could be used for imaging changes in endogenous pH induced by dexamethanose (DMT) in the endoplasmic reticulum.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society
ID Code:134520
Deposited On:09 Jan 2023 03:33
Last Modified:09 Jan 2023 03:33

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