Hajra, Dipasree ; Datey, Akshay ; Chakravortty, Dipshikha (2020) Attenuation Methods for Live Vaccines Vaccine Delivery Technology, 2183 . pp. 331-356. ISSN 1064-3745
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Official URL: http://doi.org/10.1007/978-1-0716-0795-4_17
Related URL: http://dx.doi.org/10.1007/978-1-0716-0795-4_17
Abstract
Vaccination was developed by Edward Jenner in 1796. Since then, vaccination and vaccine development research has been a hotspot of research in the scientific community. Various ways of vaccine development are successfully employed in mass production of vaccines. One of the most successful ways to generate vaccines is the method of virulence attenuation in pathogens. The attenuated strains of viruses, bacteria, and parasites are used as vaccines which elicit robust immune response and confers protection against virulent pathogens. This chapter brings together the most common and efficient ways of generating live attenuated vaccine strains in viruses, bacteria, and parasites.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Springer Nature Switzerland AG |
| Keywords: | Live attenuated strains;Gene inactivation;Mutagenesis;Irradiation;microRNA |
| ID Code: | 133155 |
| Deposited On: | 27 Dec 2022 04:02 |
| Last Modified: | 27 Dec 2022 04:02 |
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