Synthesis of 3-Arylisocoumarins by Using Acyl Anion Chemistry and Synthesis of Thunberginol A and Cajanolactone A

Sudarshan, Kasireddy ; Manna, Manash Kumar ; Aidhen, Indrapal Singh (2015) Synthesis of 3-Arylisocoumarins by Using Acyl Anion Chemistry and Synthesis of Thunberginol A and Cajanolactone A European Journal of Organic Chemistry, 2015 (8). pp. 1797-1803. ISSN 1434-193X

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Official URL: http://doi.org/10.1002/ejoc.201403524

Related URL: http://dx.doi.org/10.1002/ejoc.201403524

Abstract

3-Arylisocoumarins are synthesized by using a new strategy based on acyl anion chemistry. Aryl-substituted α-aminonitriles are used as acyl anion equivalents in this study. Further, the route is general and can be applied to the synthesis of 8-hydroxy-3-arylisocoumarins, including thunberginol A and cajanolactone A, which are naturally occurring isocoumarins known for their biological activities. DBU = 1,8-diazabicyclo[5.4.0]undec-7-ene.

Item Type:Article
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ID Code:131874
Deposited On:09 Dec 2022 06:36
Last Modified:09 Dec 2022 06:36

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