Stereoselective synthesis of the C1–C20 segment of the microsclerodermins A and B

Chandrasekhar, S. ; Sultana, S. Shameem (2006) Stereoselective synthesis of the C1–C20 segment of the microsclerodermins A and B Tetrahedron Letters, 47 (40). pp. 7255-7258. ISSN 00404039

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Official URL: http://doi.org/10.1016/j.tetlet.2006.07.107

Related URL: http://dx.doi.org/10.1016/j.tetlet.2006.07.107

Abstract

An enantioselective route for the synthesis of key fragment C1–C20 resident in microsclerodermins A and B is described. The route features deoxygenative rearrangement of an hydroxy-alkynoate and a highly enantio- and diastereo-controled iterative dihydroxylation as key reactions, starting from S-(−)-citronellol.

Item Type:Article
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ID Code:131496
Deposited On:07 Dec 2022 03:35
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