Stereoselective synthesis of (−)-bulgecinine hydrochloride and its C-2 epimer from l-ascorbic acid

Chandrasekhar, Srivari ; Chandrashekar, Gudise ; Vijeender, Kandi ; Sarma, Ganti Dattatreya (2006) Stereoselective synthesis of (−)-bulgecinine hydrochloride and its C-2 epimer from l-ascorbic acid Tetrahedron: Asymmetry, 17 (20). pp. 2864-2869. ISSN 09574166

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Official URL: http://doi.org/10.1016/j.tetasy.2006.10.033

Related URL: http://dx.doi.org/10.1016/j.tetasy.2006.10.033

Abstract

An efficient strategy for the stereocontrolled synthesis of (−)-bulgecinine hydrochloride 1 was accomplished by utilizing a Wittig Horner olefination, stereoselective reduction of the double bond and intramolecular N-alkylation to furnish the target.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Ltd
ID Code:131495
Deposited On:07 Dec 2022 03:33
Last Modified:07 Dec 2022 03:33

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