Alkylative elimination of α,β-epoxy tosylhydrazones

Chandrasekhar, S. ; Takhi, Mohamed ; Yadav, J.S. (1995) Alkylative elimination of α,β-epoxy tosylhydrazones Tetrahedron Letters, 36 (2). pp. 307-310. ISSN 00404039

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Official URL: http://doi.org/10.1016/0040-4039(94)02237-6

Related URL: http://dx.doi.org/10.1016/0040-4039(94)02237-6

Abstract

Optically pure allyl alcohols have been prepared from tosylhydrazones derived from chiral epoxy aldehydes by alkylative elimination utilizing alkyl magnesium reagents. α, β-Epoxy tosylhydrazones undergo alkylative fragmentation in the presence of alkyl magnesium reagents to yield the chiral-(E)-allyl alcohols.

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Deposited On:07 Dec 2022 02:54
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