Yadav, J.S. ; Sarkar, Sanjita ; Chandrasekhar, S. (1999) A convergent total synthesis of mappicine ketone: A leading antiviral compound Tetrahedron, 55 (17). pp. 5449-5456. ISSN 00404020
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Official URL: http://doi.org/10.1016/S0040-4020(99)00191-X
Related URL: http://dx.doi.org/10.1016/S0040-4020(99)00191-X
Abstract
An efficient total synthesis of the naturally occuring mappicine ketone 1 and mappicine 2 are described. The approach is based on the assembly of tricyclic amine 5 with pseudo acid chloride 20. A Friedlander condensation is utilized for the construction of the ABC skeleton and a periselective Diels-Alder approach is utilized for the preparation of the pseudo acid chloride. An efficient total synthesis of the naturally occuring antiviral compound mappicine ketone is reported.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Ltd |
| ID Code: | 131440 |
| Deposited On: | 06 Dec 2022 13:26 |
| Last Modified: | 06 Dec 2022 13:26 |
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