Chandrasekhar, S. ; Mohanty, Pradyumna K. (1999) Stereoselective synthesis of (+)-CP-99,994: A substance P non-peptide antagonist Tetrahedron Letters, 40 (27). pp. 5071-5072. ISSN 00404039
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Official URL: http://doi.org/10.1016/S0040-4039(99)00983-1
Related URL: http://dx.doi.org/10.1016/S0040-4039(99)00983-1
Abstract
A highly stereoflexible total synthesis of (+)-CP-99,994 is achieved starting, from (S)-serine, key steps being a diastereoselective Grignard addition, a one-pot reductive protection of an azide, and one-pot oxidative Wittig olefination.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Ltd |
| ID Code: | 131439 |
| Deposited On: | 06 Dec 2022 13:25 |
| Last Modified: | 06 Dec 2022 13:25 |
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