Ruthenium-catalyzed benzimidazoisoquinoline synthesis via oxidative coupling of 2-arylbenzimidazoles with alkynes

Kavitha, Nerella ; Sukumar, Genji ; Kumar, Vemula Praveen ; Mainkar, Prathama S. ; Chandrasekhar, Srivari (2013) Ruthenium-catalyzed benzimidazoisoquinoline synthesis via oxidative coupling of 2-arylbenzimidazoles with alkynes Tetrahedron Letters, 54 (32). pp. 4198-4201. ISSN 00404039

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Official URL: http://doi.org/10.1016/j.tetlet.2013.05.106

Related URL: http://dx.doi.org/10.1016/j.tetlet.2013.05.106

Abstract

Synthesis of a fused bis-heterocyclic framework, benzimidazoisoquinoline, has been achieved using Ru-catalyzed reaction of alkynes with 2-aryl benzimidazoles in the presence of Cu salts. The method provides an easy access for the generation of a library of benzimidazoisoquinoline derivatives.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Ltd
Keywords:Oxidative coupling;Benzimidazoisoquinoline;C–H activation;PEG-400
ID Code:131345
Deposited On:06 Dec 2022 10:50
Last Modified:06 Dec 2022 10:50

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