Multicomponent reactions in PEG-400: ruthenium-catalyzed synthesis of substituted pyrroles

Chandrasekhar, Srivari ; Patro, Vidyavathi ; Chavan, Lahu N. ; Chegondi, Rambabu ; Grée, René (2014) Multicomponent reactions in PEG-400: ruthenium-catalyzed synthesis of substituted pyrroles Tetrahedron Letters, 55 (43). pp. 5932-5935. ISSN 00404039

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Official URL: http://doi.org/10.1016/j.tetlet.2014.08.105

Related URL: http://dx.doi.org/10.1016/j.tetlet.2014.08.105

Abstract

An efficient and eco-friendly method for the synthesis of substituted pyrroles has been developed via ruthenium-catalyzed multicomponent reaction of ketone, amine, and ethylene glycol in PEG-400 as solvent medium without using any external ligand. The catalytic system and solvent can be recycled with the same, as well as different, ketones with minimum loss of Ru-catalyst activity.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Ltd
Keywords:Pyrrole;Multicomponent reaction;Ruthenium;Eco-friendly;Polyethylene glycol (PEG-400)
ID Code:131326
Deposited On:06 Dec 2022 10:18
Last Modified:06 Dec 2022 10:18

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