Total synthesis of a thromboxane receptor antagonist, terutroban

Ahmed, Wasim ; Mainkar, Prathama S. ; Pabbaraja, Srihari ; Chandrasekhar, Srivari (2015) Total synthesis of a thromboxane receptor antagonist, terutroban Organic & Biomolecular Chemistry, 13 (10). pp. 2951-2957. ISSN 1477-0520

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Official URL: http://doi.org/10.1039/C4OB02302A

Related URL: http://dx.doi.org/10.1039/C4OB02302A

Abstract

A total synthesis of terutroban is achieved using the Claisen rearrangement, Friedel–Crafts acylation and Heck coupling as key reactions, avoiding the classical Diels–Alder approach used before.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry
ID Code:131323
Deposited On:06 Dec 2022 10:14
Last Modified:06 Dec 2022 10:14

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