Synthetic Strategy toward the Pentacyclic Core of Melodinus Alkaloids

Goli, Navya ; Kallepu, Shivakrishna ; Mainkar, Prathama S. ; Lakshmi, Jerripothula K. ; Chegondi, Rambabu ; Chandrasekhar, Srivari (2018) Synthetic Strategy toward the Pentacyclic Core of Melodinus Alkaloids The Journal of Organic Chemistry, 83 (4). pp. 2244-2249. ISSN 0022-3263

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Official URL: http://doi.org/10.1021/acs.joc.7b03138

Related URL: http://dx.doi.org/10.1021/acs.joc.7b03138

Abstract

The three-component Povarov reaction is efficiently utilized for construction of the pentacyclic framework of complex Melodinus alkaloids, which is amenable to expansion to other complex natural products. The key steps were Povarov reaction, one-pot reductive cyclization, and ring-closing metathesis (RCM) reaction.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society
ID Code:131298
Deposited On:06 Dec 2022 09:21
Last Modified:06 Dec 2022 09:21

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