Benzyne Insertion onto β-Keto Esters of Polycyclic Natural Products: Synthesis of Benzo Octacyclo Scaffolds

Kallepu, Shivakrishna ; Sanjeev, Karekar ; Chegondi, Rambabu ; Mainkar, Prathama S. ; Chandrasekhar, Srivari (2018) Benzyne Insertion onto β-Keto Esters of Polycyclic Natural Products: Synthesis of Benzo Octacyclo Scaffolds Organic Letters, 20 (22). pp. 7121-7124. ISSN 1523-7060

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Official URL: http://doi.org/10.1021/acs.orglett.8b03070

Related URL: http://dx.doi.org/10.1021/acs.orglett.8b03070

Abstract

Benzyne insertion to build the privileged scaffold of a [6.8.6]-tricyclic framework on polycyclic and sp3-rich natural products has been developed. The formation of the [6.8.6]-tricyclic ring system is solvent dependent.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society
ID Code:131293
Deposited On:06 Dec 2022 09:13
Last Modified:06 Dec 2022 09:13

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