Metal Free Domino β-Azidation/[3 + 2] Cycloaddition Reaction for the Synthesis of 1,2,3-Triazole-Fused Dihydrobenzoxazinones

Donikela, Sangeetha ; Mainkar, Prathama S. ; Nayani, Kiranmai ; Chandrasekhar, Srivari (2019) Metal Free Domino β-Azidation/[3 + 2] Cycloaddition Reaction for the Synthesis of 1,2,3-Triazole-Fused Dihydrobenzoxazinones The Journal of Organic Chemistry, 84 (16). pp. 10546-10553. ISSN 0022-3263

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Official URL: http://doi.org/10.1021/acs.joc.9b01660

Related URL: http://dx.doi.org/10.1021/acs.joc.9b01660

Abstract

A metal free DBU catalyzed synthesis of 1,2,3-triazole-fused dihydrobenzoxazinone derivatives by tandem β-azidation/[3 + 2] cycloaddition reaction has been developed under mild conditions. The methodological studies offer a broad scope and proceed well with a wide range of alkynylated cyclohexa 2,5-dienones, giving new cis-triazole-fused tricyclic scaffolds.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society
ID Code:131287
Deposited On:06 Dec 2022 09:03
Last Modified:06 Dec 2022 09:03

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