C12-Helix Development in (αγ)nSequences - Spectroscopic Characterization of Boc-[Aib-γ4(R)Val]-OMe Oligomers

Dinesh, Bhimareddy ; Vinaya, Vishwanathan ; Raghothama, Srinivasarao ; Balaram, Padmanabhan (2013) C12-Helix Development in (αγ)nSequences - Spectroscopic Characterization of Boc-[Aib-γ4(R)Val]-OMe Oligomers European Journal of Organic Chemistry, 2013 (17). pp. 3590-3596. ISSN 1434-193X

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Official URL: http://doi.org/10.1002/Ejoc.201300264

Related URL: http://dx.doi.org/10.1002/Ejoc.201300264

Abstract

The formation of C12-helical structures in the hybrid αγ oligopeptides Boc–[Aib–γ4(R)Val]n–OMe in solution is demonstrated by NMR and IR methods. The intramolecularly hydrogen-bonded solution conformations resemble those previously determined by X-ray crystallography. C12-helix development has also been monitored by far-UV CD.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons.
ID Code:131223
Deposited On:06 Dec 2022 04:45
Last Modified:30 Jan 2023 10:35

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