Gharpure, Santosh J. ; Prasad, J. V. K. ; Bera, Kalisankar (2014) Tandem Nucleophilic Addition/Oxa-Michael Reaction for the Synthesis ofcis-2,6-Disubstituted Tetrahydropyrans European Journal of Organic Chemistry, 2014 (17). pp. 3570-3574. ISSN 1434-193X
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Official URL: http://doi.org/10.1002/ejoc.201402199
Related URL: http://dx.doi.org/10.1002/ejoc.201402199
Abstract
A Lewis acid catalyzed tandem nucleophilic addition/oxa-Michael reaction is developed for the synthesis of cis-2,6-disubstituted tetrahydropyran (THP) derivatives in good yields with excellent diastereoselectivities. The strategy is successfully used in the construction of THP derivatives with three stereocenters in a highly stereoselective fashion.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons. |
| ID Code: | 130985 |
| Deposited On: | 02 Dec 2022 05:09 |
| Last Modified: | 02 Dec 2022 05:09 |
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