Harikrishna, Kommidi ; Mukkamala, Ramesh ; Hinkelmann, Bettina ; Sasse, Florenz ; Aidhen, Indrapal Singh (2013) Iodine-Promoted Oxidative Conversion ofo-Vinyl Diaryl Ketones intoo-Acetyl Diaryl Ketones, Synthesis of 1-Methyl-4-arylphthalazines as Analogues of Podophyllotoxin European Journal of Organic Chemistry, 2014 (5). pp. 1066-1075. ISSN 1434-193X
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Official URL: http://doi.org/10.1002/ejoc.201301159
Related URL: http://dx.doi.org/10.1002/ejoc.201301159
Abstract
A new method is described for the metal-free oxidation of o-vinyl diaryl ketones in the presence of molecular iodine or N-iodosuccinimide to give o-acetyl diaryl ketones. 1-Methyl-4-arylphthalazines were synthesized as analogues of podophyllotoxin, and the antiproliferative activity of these derivatives on mammalian cell lines was studied.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons. |
| ID Code: | 130978 |
| Deposited On: | 02 Dec 2022 04:49 |
| Last Modified: | 02 Dec 2022 04:49 |
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