SnCl4/Sn catalyzed chemoselective reduction of glycopyranosyl azides for the synthesis of diversely functionalized glycopyranosyl chloroacetamides

Sahoo, Laxminarayan ; Singhamahapatra, Anadi ; Paul, Katuri J.V. ; Loganathan, Duraikkannu (2013) SnCl4/Sn catalyzed chemoselective reduction of glycopyranosyl azides for the synthesis of diversely functionalized glycopyranosyl chloroacetamides Tetrahedron Letters, 54 (39). pp. 5361-5365. ISSN 0040-4039

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Official URL: http://doi.org/10.1016/j.tetlet.2013.07.110

Related URL: http://dx.doi.org/10.1016/j.tetlet.2013.07.110

Abstract

A method for the chemoselective reduction of glycopyranosyl azides using SnCl4 and tin metal as the reducing agent followed by in situ chloroacetylation of the synthesized glycopyranosyl amine was developed. This reaction is applicable to diversely functionalized glycopyranosyl azides for the synthesis of glycopyranosyl chloroacetamides.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Glycopyranosyl azide; In situ reduction; Chloroacetylation; Functionalized glycoconjugates
ID Code:130527
Deposited On:25 Nov 2022 10:54
Last Modified:25 Nov 2022 10:54

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