Stereoselective Synthesis of Substituted 1,4-Oxazepanes by Intramolecular Reductive Etherification

Gharpure, Santosh J. ; Prasad, J. V. K. (2013) Stereoselective Synthesis of Substituted 1,4-Oxazepanes by Intramolecular Reductive Etherification European Journal of Organic Chemistry, 2013 (11). pp. 2076-2079. ISSN 1434-193X

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Official URL: http://doi.org/10.1002/ejoc.201300135

Related URL: http://dx.doi.org/10.1002/ejoc.201300135

Abstract

A facile and general strategy is developed for the stereoselective synthesis of substituted 1,4-oxazepane derivatives through an intramolecular reductive etherification reaction. The effects of the substituents present on the oxonium ion and the position of this ion with respect to the nitrgen atom on the yield and selectivity of the reaction are also studied.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons.
ID Code:130305
Deposited On:24 Nov 2022 06:08
Last Modified:24 Nov 2022 06:08

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