A Defunctionalization Concept for the Convenient Synthesis of Bis(5-arylfuran-2-yl)methane Scaffolds

Tiwari, Praveen Kumar ; Mukhopadhyay, Tufan ; Aidhen, Indrapal Singh (2013) A Defunctionalization Concept for the Convenient Synthesis of Bis(5-arylfuran-2-yl)methane Scaffolds European Journal of Organic Chemistry, 2013 (36). pp. 8083-8086. ISSN 1434-193X

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Official URL: http://doi.org/10.1002/ejoc.201301319

Related URL: http://dx.doi.org/10.1002/ejoc.201301319

Abstract

Formation of bis(5-arylfuran-2-yl)methane scaffold 1 has been achieved by using a defunctionalization concept involving aryl ketones 2 under the influence of acid. Ketones 2 are easily accessible from L-(+)-tartaric acid through an umpolung strategy using α-amino nitriles as acyl anion equivalents. The stereocomponent (threo/erythro) present in 2 was not significant for this transformation.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons.
ID Code:130302
Deposited On:24 Nov 2022 06:01
Last Modified:24 Nov 2022 06:01

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