Active ion transporters from readily accessible acyclic octapeptides containing 3-aminobenzoic acid and alanine

Benke, Bahiru P. ; Madhavan, Nandita (2013) Active ion transporters from readily accessible acyclic octapeptides containing 3-aminobenzoic acid and alanine Chemical Communications, 49 (66). p. 7340. ISSN 1359-7345

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Official URL: http://doi.org/10.1039/C3CC44224A

Related URL: http://dx.doi.org/10.1039/C3CC44224A

Abstract

Ion transporters have been developed from acyclic octapeptides comprising L/D alanine and m-aminobenzoic acid. These octapeptides transport cations up to 3 times faster than their cyclic analog through lipid vesicles. Preliminary CD, XRD and computational studies allude to a 6–9 Å wide tetrameric ion channel as the active ion transporter.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry.
ID Code:130256
Deposited On:23 Nov 2022 11:12
Last Modified:07 Dec 2022 04:06

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