Design and synthesis of azobenzene template based sulfonamide for capture of HCAII: dependence of efficiency on E–Z geometry

Addy, Partha Sarathi ; Saha, Baisakhee ; Panja, Arpita ; Das, Amit Kumar ; Basak, Amit (2014) Design and synthesis of azobenzene template based sulfonamide for capture of HCAII: dependence of efficiency on E–Z geometry Tetrahedron Letters, 55 (16). pp. 2625-2628. ISSN 0040-4039

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Official URL: http://doi.org/10.1016/J.Tetlet.2014.02.124

Related URL: http://dx.doi.org/10.1016/J.Tetlet.2014.02.124

Abstract

We report the synthesis of azobenzene template based sulfonamides 1 and 2 for capture of Human Carbonic Anhydrase II (HCAII). Out of these, 1 showed successful capturing of the protein, only when it is photo-isomerized to the Z form thus demonstrating the importance of spatial proximity of the reactive and selective functionalities.

Item Type:Article
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ID Code:129956
Deposited On:05 Dec 2022 05:36
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