Remarkable photocytotoxicity of curcumin in HeLa cells in visible light and arresting its degradation on oxovanadium(iv) complex formation

Banerjee, Samya ; Prasad, Puja ; Hussain, Akhtar ; Khan, Imran ; Kondaiah, Paturu ; Chakravarty, Akhil R. (2012) Remarkable photocytotoxicity of curcumin in HeLa cells in visible light and arresting its degradation on oxovanadium(iv) complex formation Chemical Communications, 48 (62). p. 7702. ISSN 1359-7345

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Official URL: http://doi.org/10.1039/C2CC33576J

Related URL: http://dx.doi.org/10.1039/C2CC33576J

Abstract

Curcumin (Hcur) as a cellular imaging and PDT agent shows remarkable photocytotoxicity in HeLa cells in visible light of 400–700 nm giving IC50 = 8.2 ± 0.2 μM and its degradation is arrested on formation of photocytotoxic dipyridophenazine (dppz) complex [VO(cur)(dppz)Cl] (IC50 = 3.3 ± 0.4 μM), while both are less toxic in the dark.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry
ID Code:129786
Deposited On:21 Nov 2022 05:26
Last Modified:21 Nov 2022 05:26

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