Jain, D. V. S. ; Kashid, N. ; Kapoor, S. ; Chadha, R. (2000) Enthalpies of solution of ampicillin, amoxycillin and their binary mixtures at 310.15 K International Journal of Pharmaceutics, 201 (1). pp. 1-6. ISSN 0378-5173
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S03785...
Related URL: http://dx.doi.org/10.1016/S0378-5173(00)00387-2
Abstract
Enthalpies of solutions of ampicillin, amoxycillin and their binary mixtures have been determined at pH 2, 5, and 7 using C-80 calorimeter. The systems showed endothermic behaviour; molar enthalpies of solutions of ampicillin were determined to be 13.32, 15.89 and 23.21 kJ mol-1 and amoxycillin were 16.32, 18.45 and 26.25 kJ mol-1 at pH 2, 5, and 7, respectively. The excess molar enthalpies of solution have also been calculated to find any interaction between these two drugs.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Ampicillin; Amoxycillin; Binary Mixture; Calorimeter; Enthalpy of Solution; Excess Molar Enthalpy |
| ID Code: | 12923 |
| Deposited On: | 11 Nov 2010 08:25 |
| Last Modified: | 03 Jun 2011 06:47 |
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