Strategies to manage hepatitis C virus (HCV) infection disease burden - volume 2

Gane, E. ; Kershenobich, D. ; Seguin-Devaux, C. ; Kristian, P. ; Aho, I. ; Dalgard, O. ; Shestakova, I. ; Nymadawa, P. ; Blach, S. ; Acharya, S. ; Anand, A. C. ; Andersson, M. I. ; Arendt, V. ; Arkkila, P. ; Baatarkhuu, O. ; Barclay, K. ; Ben-Ari, Z. ; Bergin, C. ; Bessone, F. ; Blokhina, N. ; Brunton, C. R. ; Choudhuri, G. ; Chulanov, V. ; Cisneros, L. ; Croes, E. A. ; Dahgwahdorj, Y. A. ; Daruich, J. R. ; Dashdorj, N. R. ; Davaadorj, D. ; de Knegt, R. J. ; de Vree, M. ; Gadano, A. C. ; Gower, E. ; Halota, W. ; Hatzakis, A. ; Henderson, C. ; Hoffmann, P. ; Hornell, J. ; Houlihan, D. ; Hrusovsky, S. ; Jarčuška, P. ; Kostrzewska, K. ; Leshno, M. ; Lurie, Y. ; Mahomed, A. ; Mamonova, N. ; Mendez-Sanchez, N. ; Mossong, J. ; Norris, S. ; Nurmukhametova, E. ; Oltman, M. ; Oyunbileg, J. ; Oyunsuren, Ts. ; Papatheodoridis, G. ; Pimenov, N. ; Prins, M. ; Puri, P. ; Radke, S. ; Rakhmanova, A. ; Razavi, H. ; Razavi-Shearer, K. ; Reesink, H. W. ; Ridruejo, E. ; Safadi, R. ; Sagalova, O. ; Sanchez Avila, J. F. ; Sanduijav, R. ; Saraswat, V. ; Schréter, I. ; Shah, S. R. ; Shevaldin, A. ; Shibolet, O. ; Silva, M. O. ; Sokolov, S. ; Sonderup, M. ; Souliotis, K. ; Spearman, C. W. ; Staub, T. ; Stedman, C. ; Strebkova, E. A. ; Struck, D. ; Sypsa, V. ; Tomasiewicz, K. ; Undram, L. ; van der Meer, A. J. ; van Santen, D. ; Veldhuijzen, I. ; Villamil, F. G. ; Willemse, S. ; Zuckerman, E. ; Zuure, F. R. ; Prabdial-Sing, N. ; Flisiak, R. ; Estes, C. (2015) Strategies to manage hepatitis C virus (HCV) infection disease burden - volume 2 Journal of Viral Hepatitis, 22 . pp. 46-73. ISSN 13520504

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Official URL: http://doi.org/10.1111/jvh.12352

Related URL: http://dx.doi.org/10.1111/jvh.12352

Abstract

The hepatitis C virus (HCV) epidemic was forecasted through 2030 for 15 countries, and the relative impact of two scenarios was considered: (i) increased treatment efficacy while holding the treated population constant and (ii) increased treatment efficacy and increased annual treated population. Increasing levels of diagnosis and treatment, in combination with improved treatment efficacy, were critical for achieving substantial reductions in disease burden. In most countries, the annual treated population had to increase several fold to achieve the largest reductions in HCV-related morbidity and mortality. This suggests that increased capacity for screening and treatment will be critical in many countries. Birth cohort screening is a helpful tool for maximizing resources. In most of the studied countries, the majority of patients were born between 1945 and 1985.

Item Type:	Article
Source:	Copyright of this article belongs to John Wiley & Sons, Inc.
Keywords:	HCV; diagnosis; disease burden; epidemiology; hepatitis C; incidence; mortality; prevalence; scenarios; treatment
ID Code:	128927
Deposited On:	22 Nov 2022 09:35
Last Modified:	22 Nov 2022 09:35

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