Nair, Vijay ; Sreekanth, A.R ; Biju, A.T ; Rath, Nigam P (2003) The reaction of isoquinoline and dimethyl acetylenedicarboxylate with 1,2- and 1,4-benzoquinones: a novel synthesis of spiro[1,3]oxazino[2,3-a]isoquinolines Tetrahedron Letters, 44 (4). pp. 729-732. ISSN 00404039
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Official URL: http://doi.org/10.1016/S0040-4039(02)02649-7
Related URL: http://dx.doi.org/10.1016/S0040-4039(02)02649-7
Abstract
The 1,4-dipolar intermediate generated by the addition of isoquinoline to dimethyl acetylenedicarboxylate is trapped by 1,2- and 1,4-benzoquinones to afford spiro[1,3]oxazino[2,3-a]isoquinoline derivatives in high yields. A novel three component reaction of isoquinoline and dimethyl acetylenedicarboxylate with 1,2- and 1,4-benzoquinones, afford spiro[1,3]oxazino[2,3-a]isoquinoline derivatives in high yields.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science Ltd. |
| ID Code: | 128761 |
| Deposited On: | 03 Nov 2022 06:58 |
| Last Modified: | 03 Nov 2022 06:58 |
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