Facile Synthesis of γ-Ketophosphonates by an Intermolecular Stetter Reaction onto Vinylphosphonates

Patra, Atanu ; Bhunia, Anup ; Biju, Akkattu T. (2014) Facile Synthesis of γ-Ketophosphonates by an Intermolecular Stetter Reaction onto Vinylphosphonates Organic Letters, 16 (18). pp. 4798-4801. ISSN 1523-7060

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Official URL: http://doi.org/10.1021/ol502262d

Related URL: http://dx.doi.org/10.1021/ol502262d

Abstract

The atom-economic and practical N-heterocyclic carbene (NHC) catalyzed Stetter reaction for the synthesis of γ-ketophosphonates by the reaction of aromatic aldehydes with vinylphosphonates is reported. The NHC derived from N-mesitylimidazolium salt (IMes) was an effective catalyst for this transformation, and the products were formed in moderate to good yields.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society
ID Code:128680
Deposited On:03 Nov 2022 06:53
Last Modified:03 Nov 2022 06:53

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