Recent Advances in the N-Heterocyclic Carbene (NHC)-Organocatalyzed Stetter Reaction and Related Chemistry

Biju, Akkattu ; Yetra, Santhivardhana ; Patra, Atanu (2015) Recent Advances in the N-Heterocyclic Carbene (NHC)-Organocatalyzed Stetter Reaction and Related Chemistry Synthesis, 47 (10). pp. 1357-1378. ISSN 0039-7881

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Official URL: http://doi.org/10.1055/s-0034-1378692

Related URL: http://dx.doi.org/10.1055/s-0034-1378692

Abstract

Recent developments in the N-heterocyclic carbene (NHC)-catalyzed umpolung of aldehydes followed by their interception with activated carbon–carbon double bonds, namely the Stetter reaction, are presented. Advances in the inter- and intramolecular versions of this reaction, enantioselective transformations as well as the use of unactivated olefins in this type of reaction are discussed.

Item Type:Article
Source:Copyright of this article belongs to Georg Thieme Verlag KG
Keywords:N-heterocyclic carbenes - Stetter reaction - organocatalysis - umpolung - asymmetric catalysis
ID Code:128677
Deposited On:03 Nov 2022 06:51
Last Modified:11 Nov 2022 05:26

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