Roy, Tony ; Thangaraj, Manikandan ; Gonnade, Rajesh G. ; Biju, Akkattu T. (2016) Synthesis of functionalized amino epoxides by a three-component coupling involving aziridines, arynes and aldehydes Chemical Communications, 52 (58). pp. 9044-9047. ISSN 1359-7345
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Official URL: http://doi.org/10.1039/C6CC00057F
Related URL: http://dx.doi.org/10.1039/C6CC00057F
Abstract
A transition-metal-free three-component coupling involving N-substituted aziridines, arynes and aldehydes resulting in the formation of trisubstituted N-aryl α-amino epoxides has been demonstrated. The reaction likely proceeds via the highly strained cyclic nitrogen ylide intermediates generated from aziridines and arynes.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Royal Society of Chemistry |
| ID Code: | 128659 |
| Deposited On: | 03 Nov 2022 06:52 |
| Last Modified: | 03 Nov 2022 06:52 |
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